Personally I have always used adhesive and shot regular nails, criss crossing as someone else mentioned. Never had an issue nailing into the metal studs as well.
Only exception is a large heavy crown, in that case I have ripped backing to match the angle, and screwed it into the metal framing, doesn't take that long and the crown is real easy to install, can be nailed anywhere along it, and nails nice and tight.
Will have to try out the self tapping trim head screws, I've used them for exterior stuff but never for interior finishing.